How CRISPR-Cas9 Actually Works
CRISPR and the Gene Revolution
Bacterial immune system → molecular scissors + GPS. sgRNA, Cas9, repair mechanisms. How it corrects sickle cell.
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Learning Material
6 pagesLesson 4 — How CRISPR-Cas9 Actually Works
Understanding the Complex: CRISPR and the Gene Revolution
The anchor:
A single mutation — one wrong letter in the hemoglobin gene — gives Victoria Gray sickle cell disease. CRISPR found that letter and changed it.
Here's how.