University · Chemical Engineering · Biochemical Engineering

Cell Culture Technology and Mammalian Cell Bioreactors

4 Abschnitte

Chinese hamster ovary (CHO) cell culture for monoclonal antibody production, fed-batch vs perfusion bioreactor modes, cell retention devices (tangential flow filtration), growth kinetics and nutrient feeding strategies, cell viability and product quality attributes (glycosylation), shear sensitivity and sparger design for mammalian cells.

Inhaltsübersicht

  • CHO Cells and Monoclonal Antibody Production
  • Fed-Batch and Perfusion Bioreactor Modes
  • Cell Retention Devices and Shear Sensitivity
  • Glycosylation as a Critical Quality Attribute: Control and Analytics
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