University · Neuroscience · Cellular and Molecular Neuroscience

Gene Expression and Epigenetics in the Brain

4 Abschnitte

How neural activity regulates gene transcription via CREB and immediate early genes, and how epigenetic mechanisms — DNA methylation, histone modifications, and non-coding RNAs — encode lasting changes in neuronal function, underlie experience-dependent plasticity, and may be transmitted across generations.

Inhaltsübersicht

Activity-Dependent Transcription: CREB and Immediate Early Genes
DNA Methylation and Histone Modifications in Neurons
Experience-Dependent Epigenetic Changes and Brain Plasticity
Transgenerational Epigenetics and Therapeutic Implications

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