University · Neuroscience · Cellular and Molecular Neuroscience

Long-Term Potentiation and Synaptic Plasticity Mechanisms

4 Abschnitte

Discovery and mechanistic dissection of LTP: NMDA receptor coincidence detection, CaMKII signaling, AMPA receptor trafficking, early versus late LTP, synaptic tagging, and metaplasticity.

Inhaltsübersicht

Discovery of LTP: Bliss and Lømo 1973 and the Hippocampal Preparation
NMDA Receptor as Coincidence Detector: Mg²⁺ Block, Ca²⁺ Influx, and Hebbian Plasticity
CaMKII, AMPA Receptor Trafficking, and Early LTP Expression
Late LTP, Synaptic Tagging, Metaplasticity, and the BCM Theory

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